ea0056p455 | Diabetes complications | ECE2018
Jude Edward
, Mascarenhas Janice
, Bhatnagar Deepak
, Weston R
, Wilkinson Fiona
, Alexander Yvonne
Type 2 diabetes mellitus (T2DM) and obesity are linked to osteoporosis, making these patients at increased risk of developing fractures. In this study we aimed to investigate bone biochemical markers and bone structure in diabetic patients to compare with non-diabetic controls.Methods: We recruited 21 type 2 diabetic patients and 10 non-diabetic controls. Fasting blood samples were collected for markers of bone turnover (Sclerostin (SCL), RANKL, OPG, OPN...